Questions About Cat Kidney Disease?


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Kidney Disease in cats.

Chronic renal failure, or kidney disease in cats, is a very common condition in cats. This is
especially the case in older cats. Often chronic renal failure will advance over time so that
there is a gradual worsening of the cat disease. Treatment of the disease and support can
benefit the quality of life and longevity of life by reducing the evolution of the sickness.

Renal Failure Cause?
Chronic renal failure or kidney failure occurs when there has been progressive and
permanent damage to the kidneys that reduces their capacity to filter and remove waste
from the blood. Often when kidney disease is diagnosed, the precise origin of the disease is
unknown. Kidney samples taken from cats often show considerable amounts of fibrous tissue
replacing the normal kidney tissue, thereby reducing the productive kidney tissue over time.

Signs, Symptoms & Diagnosis of Kidney Disease
Kidney Disease has the potential of affecting any cat, but is often seen in older cats. The
older the cat the more frequent the disease will become. It has been estimated that around
one in five cats over 15 years of age has renal failure. Unfortunately for cats, kidney
disease is 3 times more common for them than for dogs.

Some of the important functions that the kidney provide including removing toxins from the
blood and maintaining water and salt balance in the body. Blood is constantly filtered
through the kidneys to remove the toxic waste that body functions produce. A  byproduct
that is produced in this process is urine. The kidneys also concentrate the urine by
returning water to the body, preventing dehydration.

In most cases chronic renal failure is a progressive disease with a deliberate, menacing
onset, although occasionally the signs may appear to develop very quickly. Some signs of
kidney disease are quite vague - caused in part simply from the accumulation of toxins in
the blood that would normally be extracted by the healthy kidneys. The most common signs
seen in affected cats are a poor appetite, weight loss, dehydration, lethargy and
depression. There is often an increased thirst along with increased volumes of urine being
produced (due to an inability to concentrate the urine in many affected cats). Other signs
may include a poor coat, vomiting, bad-smelling breath, ulceration in the mouth and
weakness. These symptoms will become worse over time.

As signs can be vague diagnosis of kidney disease is therefore made by collection of blood
and urine samples. Urea and creatinine, two substances in the blood – are commonly
analysed, as these are products of metabolism that are normally excreted by the kidneys.
In renal failure the blood concentration of these two products will be increased.  

Diet Is Important
Dietary management is important for cats with chronic renal failure, and there are three
main aspects to this:

Cats with kidney disease are more likely to become dehydrated (due to the reduced ability
of the kidneys to conserve water by concentrating urine). Maintaining a good fluid intake is
very important, and as cats generally gain much of their water from their food, whenever
possible, cats with chronic renal failure should be moist foods rather than dry foods.

Some promote an ideal diet for a cat with renal failure being a low protein content – many
of the toxic products that accumulate in the blood in renal failure are a result of protein
breakdown, and feeding a low protein diet will therefore help to minimize this. However,
protein restriction has to be performed with care. Too little protein in the diet can lead to
excessive weight loss that would be extremely detrimental to general health.  And some
authorities disagree with these procedures. We advise you to speak to your vet before
implementing any dietary plan.

One way to help protect the kindneys from further damage is to restrict the phosphate
content in the diet of the cat. Often cat food designed to help cats with kidney disease
have low levels of both protein and phosphates.

The prognosis for cats with renal insufficiency depends on the degree of damage the
kidneys have or more importantly, the degree of function they still have left. Fluid therapy
and drug therapy can allow cats to leave relatively happy lives for months to a couple of
years. Cats that can not be stabilized for home management carry a worse prognosis and
euthanasia should be considered. Unfortunately, if a cat lives long enough it will likely have
some degree of renal insufficiency. Regular veterinary exams and blood work in older cats
may allow us to detect these patients early and keep them happy and comfortable for
longer. Other disease that may make renal failure worse are hyperthyroidism, and
hypertension.
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